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The presence of driver alterations is linked to speedy development. Although several alterations are enriched in CLL in comparison with MBL, equally phases share the same driver composition. (

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Deep, targeted future-era sequencing has revealed that subclonal mutations (i.e., These present in just a portion of tumor cells) is often detected for all driver genes and are affiliated with immediate condition development and poor end result.11–13 This is particularly pertinent for TP53

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